Job Description Summary:

Global Medical Affairs at PTC is committed to helping health care providers make evidence-based decisions to optimize health outcomes in their patients with rare diseases. The Global Therapeutic area Lead, Metabolism is responsible for defining the Global Medical Affairs vision, strategy and tactics to support PTC's PKU business. He/she will partner with the Regional Medical Directors to identify and develop relationships with key opinion leaders (KOLs), identify treatment centers, ensure that the global medical affairs strategies and tactics for PKU are adopted and implemented at the local level and to ensure that the Global vision, strategy and tactics meet local needs. He/she collaborates with marketing colleagues, to ensure that the strategic PKU medical affairs plan is aligned with the brand strategy. He/she will partner with the global medical affairs (GMA) enabling functions (i.e. Publications, Medical Information, Medical Education, Medical Communications, etc.) to build the scientific communication platform (publications, congresses etc.), plan and execute scientific advisory boards, and create and deliver educational presentations both internally and externally. This role is viewed as the medical affairs subject matter expert on PKU and is expected to play a key role in educating KOLs, physicians, and internal colleagues. This position ensures adherence to relevant regulatory requirements and company Standard Operating Procedures (SOPs) as appropriate.Job Description:

ESSENTIAL FUNCTIONS

Primary duties/responsibilities:

• Develops and leads strategic global medical affairs activities related to PKU to support successful product development and commercialization
• Drives and supports communication and collaboration amongst regional and local Medical Affairs functions, GMA enabling functions and other teams in Commercial, Market Access, etc. to ensure well developed and executed PKU strategic plans; drives internal cross-functional partnerships for all PKU medical initiatives.
• Provides strategic direction and tactical guidance for medical activities of regional medical directors with respect to PKU
• Serves as the PKU subject matter expert in Global Medical Affairs. Partners with medical and commercial training to educate internal and external colleagues on the scientific and clinical aspects of PKU.
• Develops and finalizes global evidence generation plan in close collaboration with regional and country medical heads, GMA enabling functions and ensures alignment with other key internal stakeholders.
• Plans and leads the Investigator Initiated Studies (IIS) strategy and support the execution for PKU.
• Acts as Global Medical Lead for the Global Registry study, if one is developed.
• Effectively engages and builds relationships with PKU KOLs, internal and external stakeholders and healthcare professionals for the successful implementation of medical strategy for PKU; identifies and engages in scientific exchange with medical experts in the PKU therapeutic area.
• Serves as the strategic partner with respect to PKU to Clinical Development and Commercial Development teams.
• Represents Global Medical Affairs at international and regional scientific congresses.
• Collaborates closely with the Marketing function to provide medical input for commercial activities related to therapy.
• Plans and leads the publication strategy for PKU.
• Supervises medical information process and service from the PKU indication perspective in close collaboration with other functions in medical affairs; ensures Scientific Affairs Services offerings are appropriately utilized for PKU.

KNOWLEDGE/SKILLS/ABILITIES REQUIRED

Minimum level of education and years of relevant work experience:

• Advanced Degree Required with a minimum experience of 7 years progressively responsible experience in the pharmaceutical, biotechnology or related environment, preferably with around 5 years in medical affairs.

Special knowledge or skills needed required:

• Proven track record of successful leadership and progression within a medical affairs department working from both a strategic and tactical standpoint.
• Demonstrated ability to accurately and effectively evaluate medical/scientific literature and develop effective medical and communication strategies.
• Ability to analyze data and synthesize a compelling scientific narrative tailored to relevant audiences.
• Comprehensive understanding of compliance focus concerning medical affairs functions.
• Demonstrated track record of success supporting the commercialization of an orphan, rare disease and/or specialized drug(s).
• In-depth experience dealing with payer organizations.
• Demonstrated ability to create and lead cross-functional teams.
• Demonstrated ability to develop relationships with and influence KOLs, important customers, challenge common perceptions and implement medical affairs tools to improve patient care and outcomes.
• Experience building and maintaining KOL network and interacting with patient organizations.
• Ability to influence without direct authority.
• Proficiency with Microsoft Office.
• Excellent verbal and written communication and skills.
• Ability to take complex scientific information and communicate it clearly and effectively to diverse audiences in a clear and concise manner
• Ability to work effectively in a global, multicultural environment
• Ability to work independently and collaboratively, as required, in a fast-paced, matrixed, team environment consisting of internal and external team members.
• Analytical thinker with excellent problem-solving skills and the ability to adapt to changing priorities and deadlines.
• Excellent planning, organization and time management skills including the ability to support and prioritize multiple projects.
• Fluent in English (verbal and written).

Special knowledge or skills preferred:

• Expertise on PKU or related inborn errors of metabolism
• Experience in orphan/rare diseases, neurology and/or genetic disorders.

Travel requirements:

• 40% global travel
• Office-based or remote position with travel to PTC offices and off-site meetings as needed.

EEO Statement:

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PTC Therapeutics is an equal opportunity employer. We welcome applications from all individuals, regardless of race, color, national origin, gender, age, physical characteristics, social origin, disability, religion, family status, p regnancy, sexual orientation, gender identity, gender expression, disability, veteran status or any unlawful criterion under applicable law. We are committed to treating all applicants fairly and avoiding discrimination.