Post Doctoral Associate Med-Structural Biology - Pennsylvania-Pittsburgh - 24000635

Overall Summary

- - One postdoctoral position is available in Dr. Stella Y. Suns lab https://sunlab.structbio.pitt.edu/ - https://sunlab.structbio.pitt.edu/ at the University of Pittsburgh, Pittsburgh, PA. - - - We are seeking an enthusiastic postdoctoral fellow to study the cilia or flagella structures evolutionarily conserved across protists to mammals and their protein trafficking process. Their biomedical significance underlies their important roles in ciliopathies, causing numerous human diseases, and leading to various model organisms to study its assembly process. Trypanosoma brucei T. brucei, a single-celled parasite that causes African sleeping sickness, has been an emerging model organism to study flagella biogenesis. As a model system, molecular and genetic manipulation such as inducible expression and RNAi allows rapid characterization of protein functions in T. brucei. My lab is dedicated to the protein function, protein-protein interaction, and structural determination of cellular machinery in single-celled parasites by using molecular and cell biology and cutting-edge cryo-electron tomography cryo-ET with allied techniques such as cryo-FIB-SEM. With advanced imaging techniques, we can visualize the organization of cellular structures and their coordination in 3D spatial organization through a multi-scale imaging platform ranging from microns to sub-nanometers, to elucidate the molecular and structure functions that drive cell motility. Our laboratory is fully equipped for all aspects of molecular and cellular biology and has direct access to Titan Krios 3Gi, focused ion beam/scanning electron microscopy cryo-FIB-SEM Aquilos2 https://www.structbio.pitt.edu/index.php/facilities/cryoem - https://www.structbio.pitt.edu/index.php/facilities/cryoem, and other instrumentation in core facilities http://www.researchimaging.pitt.edu/content/center-biologic-imaging - http://www.researchimaging.pitt.edu/content/center-biologic-imaging.

Duties or Responsibilities

Ability to design and perform experiments

Ability to analyze and interpret experimental results

Ability to use a collaborative approach to formulate alternative and creative solutions to problems

Present research projects to internal and external meetings or workshops

Engage in writing of publications and reports

Assist with graduate student training

Good communication with group leaders and members

Expectations or Standards

Ph.D. or equivalent in molecular and cell biology, biochemistry, or structural biology. This position is subject to the Universitys background check policy.

Interested applicants should apply via the Talent Center.

Opportunities Available

Attendance of workshops, symposiums, and conferences will be supported

Postdoctoral independent funding applications will be encouraged

Postdoctoral Career Development and Progress Assessment Process https://www.oacd.health.pitt.edu/postdocs/postdoctoral-career-development-progress-assessment-process - https://www.oacd.health.pitt.edu/postdocs/postdoctoral-career-development-progress-assessment-process

Pittsburgh has great central locations, scenic views, and award-winning restaurants, offering a variety of events and things to do https://www.visitpittsburgh.com/ - https://www.visitpittsburgh.com/

The university encourages applications from under-represented groups.

The University of Pittsburgh is committed to championing all aspects of diversity, equity, inclusion, and accessibility within our community. This commitment is a fundamental value of the University and is crucial in helping us advance our mission, which includes attracting and retaining diverse workforces. We will continue to create and maintain an environment that allows individuals to discover, belong, contribute, and grow, while honoring the experiences, perspectives, and unique i entities of all.

The University of Pittsburgh is an Affirmative Action/Equal Opportunity Employer and values equality of opportunity, human dignity and diversity. EOE, including disability/vets.

Assignment Category: Full-time regular Campus: Pittsburgh Required Attachments: Cover Letter, Curriculum Vitae, Letters of Recommendation Assignment Category Full-time regular PI251000578