Arvinas is a clinical-stage biotechnology company dedicated to improving the lives of patients suffering from debilitating and life-threatening diseases through the discovery, development, and commercialization of therapies that degrade disease-causing proteins. Arvinas uses its proprietary PROTAC ® Discovery Engine platform to engineer proteolysis targeting chimeras, or PROTAC ® targeted protein degraders, that are designed to harness the body’s own natural protein disposal system to selectively and efficiently degrade and remove disease-causing proteins.

In addition to its robust preclinical pipeline of PROTAC protein degraders against validated and “undruggable” targets, the company has three investigational clinical-stage programs currently enrolling: vepdegestrant for the treatment of patients with locally advanced or metastatic ER+/HER2- breast cancer; ARV-102 for the treatment of patients with neurodegenerative disorders associated with LRRK2, and ARV-393 for the treatment of patients with relapsed/refractory non-Hodgkin Lymphoma and potentially other lymphomas.

In April 2024, Arvinas entered into a transaction with Novartis, including a global license agreement for the development and commercialization of the clinical stage PROTAC ® androgen receptor protein degrader ARV-766 for the treatment of prostate cancer. The transaction closed in May 2024.

#TeamArvinas is made up of approximately 450 passionate and curious employees, whose diverse thoughts and perspectives are highly valued. Arvinas employees embrace the freedom to pursue innovation, think creatively, and give back. They are driven by the company’s values and mission – to improve the lives of patients with serious diseases by pioneering therapies created with our revolutionary PROTAC® protein degradation platform. We’re really excited about the work we’re doing inside and outside of Arvinas, and think you will be, too. But don’t just take our word for it – learn more about life at Arvinas and what employees have to say .

For more information, please visit www.arvinas.com .

Position Summary

Arvinas has an exciting opportunity for an experienced Senior Medical Director to join our team to support our neurology pipeline. The Senior Medical Director will be a member of the Medical Affairs Leadership Team and is responsible for executing strategy and will be responsible for the development of the medical affairs plans for Arvinas’ neurology pipeline assets. The Senior Medical Director will provide strategic input to and collaborate with internal stakeholders, including those within medical affairs and cross-functional partners such as clinical development, clinical operations, research, and others as appropriate. The Senior Medical Director will also build relationships with key external experts in the fields of interest to Arvinas.

This position reports to the Vice President of Medical Affairs, and will be located remotely from a location within the U.S.

Principal Responsibilities

Key responsibilities of this role include, but are not limited to:

• Develop and drive the implementation of medical affairs plans and strategies that support and accelerate the neurology pipeline.

• Medical Affairs representation and input on asset development teams

• Oversee creation and maintenance of internal and external scientific content, including the scientific communication platform

• Lead strategy and alignment of medical affairs activities at congresses, as appropriate

• Provide Medical Affairs representation on Publication Planning Committee. Participate in data analysis efforts, and participate in manuscript, abstract, and poster development

• Collaborate closely with cross-functional partners including clinical development and clinical operations

• Provide scientific expertise within Medical Affairs subfunctions including publications, HEOR, and patient advocacy.

• Develops and maintains credible peer-to-peer relationships with external thought-leaders to inform and drive internal strategic decisions

• Plan and execute advisory boards

• Provide medical review as part of the Medical, Legal, & Regulatory (MLR) process and/or Medical Review Committee (MRC)

• As the neurology program grows, will build, lead, coach and manage a team responsible for Medical Affairs neurology activities

• Model leadership behaviors consistent with Arvinas values and mentor others in the department

• Other duties in support of the medical affairs plan, as assigned

Qualifications

• 12+ years of neurology medical affairs experience and/or relevant clinical practice preferably in the areas of neuromuscular disease, neuromodulation or movement disorders.

• Strong interpersonal skills and excellent verbal communication and presentation skills.

• Proven ability to facilitate open discussion and debate among key stakeholders and build internal and external relationships

• Experience conducting and/or presenting at advisory boards and related forums

• Experience working with cross functional medical and development teams

• Able to lead, prioritize, execute and manage several projects simultaneously

• Ability to work in a fast-paced and ever-changing environment

• Familiarity with regulatory requirements for early and late state development in neurology

• Growth mindset with demonstrated ability to perform player-coach activities

• Strong leadership skills with proven ability to grow and develop others

• Ability to travel up to 20%

• Arvinas will not be providing VISA sponsorship for this position now or in the future. You must have the ability to work without a need for current or future VISA sponsorship.

• The duties of this role are generally conducted in a home office environment. Employees must be able, with or without an accommodation to use a computer; engage in communications via phone, video, and electronic messaging; engage in problem solving and non-linear thought, analysis, and dialogue; collaborate with others; maintain general availability during standard business hours.

Education

• Doctoral degree (MD, PharmD, PhD in neuroscience or neuropsychology) required.

#LI-Remote

Arvinas is proud to offer a competitive package of base and incentive compensation as well as a comprehensive benefits program designed to support the health, wellness and financial security of our employees and their families. Benefits include group medical, vision and dental coverage, group and supplemental life insurance, and much more. To learn more about Arvinas, please visit www.arvinas.com

Arvinas is an Equal Opportunity Employer