Please apply directly on the RCUH website to be considered for the position.

POSTDOCTORAL RESEARCHER (PROTEIN ENGINEERING) - ID# 224800.

CLOSING DATE:

November 28, 2024, or until filled. Applications received after this deadline may be considered only if the position is not filled or up to the date a selection has been approved by the RCUH (whichever comes first)

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INQUIRIES: Dr. Wei Wen Su wsu@hawaii.edu.

Regular,

Full-Time, RCUH Non-Civil Service position with the Department of Molecular Biosciences and Bioengineering (MBBE), Su laboratory, located on the University of Hawaii at Manoa (UHM) campus in Honolulu, Hawaii. Continuation of employment is dependent upon program/operational needs, satisfactory work performance, availability of funds, and compliance with applicable Federal/State laws.

MONTHLY SALARY RANGE: $4,888 - $5,250/Mon.

DUTIES:

Designs and generates gene constructs, and carries out genetic transformation for expression, primarily in yeast and plant systems. Designs and engineers autoprocessing protein (AP) variants to enhance performance using synthetic biology, rational mutagenesis, and directed evolution approaches. Validates improved AP in plant using agroinfiltration. Designs and conducts genetic and biochemical tests to probe the interplay between AP expression and cellular metabolism. Engineers conditional degron to enhance induction reversibility. Utilizes AP and degron systems in metabolic engineering. Assists in supervising grad students, and in preparing manuscripts, reports, and research proposals. The Su laboratory in the Department of Molecular Biosciences and Bioengineering works on innovative research that combines rational and combinatorial protein engineering, with high-throughput screening, to develop next-generation autoprocessing protein and conditional degron systems. These cutting-edge molecular technologies propel synthetic biology, metabolic engineering, and trait engineering forward, unlocking significant applications in medicine, agriculture, and industrial biotechnology.

PRIMARY QUALIFICATIONS:

EDUCATION

PhD from an accredited college or university in Bioengineering, Biotechnology, Chemical Engineering, Biochemistry, Biophysics, Chemical Biology, Protein Chemistry, Molecular Biology, or a related STEM field. (PhD candidates may apply but must submit evidence of PhD completion upon hire).

EXPERIENCE

One to three (1-3) years of research experience in molecular biology, biochemistry, or protein chemistry. Experience may be obtained during PhD studies.

KNOWLEDGE

Strong knowledge inprotein chemistry, protein engineering, along with a robust understanding of synthetic biology, biochemistry and molecular biology

ABILITIES and SKILLS

Expert ability and skills to design and create gene constructs. Strong ability to carry out genetic transformation. Strong ability in using bioinformatic tools for protein modeling and analysis. Strong analytical skills to hypothesize, design experiments, and interpret results. Strong ability in comprehending and analyzing relevant scientific literature. Strong ability to communicate in English.

Post Offer/Employment Condition: Must be able to complete the UH Laboratory Safety training within one (1) month from date of hire. Must be able to complete the Office of Research Compliance (ORC) General Biosafety training within one (1) month from date of hire.

POLICY/REGULATORY REQUIREMENT

As a condition of employment, employee will be subject to all applicable RCUH policies, procedures, and trainings and, as applicable, subject to University of Hawaii's and/or business entity's policies, procedures, and trainings. Violation of RCUH's, UH's, or business entity's policies and/or procedures or applicab