We are seeking a highly motivated Research Technician to conduct basic and translational research in the field of oncology. Research Technician will work in Dr. Nikhil Munshi’s laboratory in the Jerome Lipper Multiple Myeloma center at Dana-Farber Cancer Institute. The Munshi Lab’s research studies focus on multiple myeloma and has transformed myeloma therapy and patient survival over the last decades through the identification and validation of therapeutic targets in tumor cells and bone marrow microenvironment.

Current projects include studies on novel molecular mechanisms underlying myeloma pathogenesis and RNA-based approaches for the treatment of myeloma.

The technician will be an integral member of our research team and will assist scientists in performing scientific research, development and/or clinical tasks of varying complexity, including set-up and monitoring experiments, making observations, calculating and recording results.

Located in Boston and the surrounding communities, Dana-Farber Cancer Institute is a leader in life changing breakthroughs in cancer research and patient care. We are united in our mission of conquering cancer, HIV/AIDS and related diseases. We strive to create an inclusive, diverse, and equitable environment where we provide compassionate and comprehensive care to patients of all backgrounds, and design programs to promote public health particularly among high-risk and underserved populations. We conduct groundbreaking research that advances treatment, we educate tomorrow's physician/researchers, and we work with amazing partners, including other Harvard Medical School-affiliated hospitals.

The role of the Research Technician is very important and critical in the flow of the laboratory’s research. Previous lab experience is encouraged as the candidate will be expected to independently carry out essential research functions in the laboratory that will include, but are not limited to:

• Cell culture

• Western blot analysis (immuno-precipitations and immunoblotting)

• RNA/DNA extractions, PCR and RT-qPCR

• Transient transfection and lentiviral transduction

• Performing cytotoxicity and proliferation assays

• Flow cytometry assays and experience with analysis (DIVA, FLOW-JO) is preferred.

• Assisting research fellows with various next-generation sequencing experiments using multiple myeloma cell lines and patient samples

• Attending lab meetings and actively participates in communicating updates on sample intake for various protocols

• Maintaining accurate electronic and physical sample inventories

• Taking charge of routine lab administration: ordering and organizing routine-use reagents

KNOWLEDGE, SKILLS AND ABILITIES REQUIRED:

• Bachelor's degree required with a major in biology or immunology preferred.

• Should have some experience of working with mice. Handling of transgenic mice will be a plus.

• Knowledge of information and techniques related to biology and immunology is preferred.

• Good organizational and interpersonal skills and a working knowledge of data management, word processing, graphic software (MS-Excel, Word, Graphpad/PRISM) is preferred.

• Basic mathematic skillset and ability to work within a team environment.

• The position is expected to work full time (40 hours/week).

At Dana-Farber Cancer Institute, we work every day to create an innovative, caring, and inclusive environment where every patient, family, and staff member feels they belong. As relentless as we are in our mission to reduce the burden of cancer for all, we are equally committed to diversifying our faculty and staff. Cancer knows no boundaries and when it comes to hiring the most dedicated and diverse professionals, neither do we. If working in this kind of organization inspires you, we encourage you to apply.

Dana-Farber Cancer Institute is an equal opportunity employer and affirms the right of every qualified applicant to receive consideration for employment without regard to race, color, religion, sex, gender identity or expression, national origin, sexual orientation, genetic information, disability, age, ancestry, military service, protected veteran status, or other characteristics protected by law.

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