Research Laboratory Tech Assoc

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Summary

Our laboratory in the Department of Internal Medicine at the University of Michigan is seeking a motivated and enthusiastic research technician to study mechanistic aspects of RNA virus infection, specifically dengue virus (DENV) and Zika virus (ZIKV). Both viruses are significant threats to human health globally. DENV is the most common human arboviral infection worldwide, causing an estimated 390 million acute infections, 500,000 hospitalizations, and 25,000 deaths each year. Like DENV, ZIKV has spread rapidly across the Americas, Africa, and Asia. My laboratory is interested in the cell biology of infection by these viruses. Specifically, we are trying to understand, at the cellular and molecular level, how these viruses hijack cells for infection and in turn, how we can interrupt viral infection by targeting this process. The laboratory has also been engaged in some research with SARS-CoV-2 (the virus that causes COVID-19) in the BSL-3 biosafety containment area at the University of Michigan.

Mission Statement

Michigan Medicine improves the health of patients, populations and communities through excellence in education, patient care, community service, research and technology development, and through leadership activities in Michigan, nationally and internationally. Our mission is guided by our Strategic Principles and has three critical components; patient care, education and research that together enhance our contribution to society.

Why Join Michigan Medicine?

Michigan Medicine is one of the largest health care complexes in the world and has been the site of many groundbreaking medical and technological advancements since the opening of the U-M Medical School in 1850. Michigan Medicine is comprised of over 30,000 employees and our vision is to attract, inspire, and develop outstanding people in medicine, sciences, and healthcare to become one of the world’s most distinguished academic health systems. In some way, great or small, every person here helps to advance this world-class institution. Work at Michigan Medicine and become a victor for the greater good.

What Benefits can you Look Forward to?

• Excellent medical, dental and vision coverage effective on your very first day

• 2:1 Match on retirement savings

Responsibilities*

Research

• Assists in research using cell culture models of RNA virus infection by performing assays, recording observations and measurements, and operating laboratory equipment

• Performs routine experimental procedures under the supervision of higher-level research staff member or principal investigator.

• Contributes to manuscripts for publication with the opportunity for coauthorship if appropriate

• If the candidate desires, there will be the option of becoming trained to work with SARS-CoV-2 at BSL-3 containment, but this is not a required responsibility. Work with SARS-CoV-2 is not expected to take up more than 25% of work hours.

Laboratory management

• Organizes laboratory inventories (e.g. plasmids, cell lines, antibodies, viral stocks)

• Keeps track of commonly used items and ordering supplies for the laboratory

• Maintains overall laboratory organization and cleanliness.

• Writes, revises, and implements standard operating procedures for laboratory equipment, chemicals and research protocols with supervision from higher-level research staff member or principal investigator

Required Qualifications*

• Bachelor’s degree in microbiology, molecular biology, cell biology, or a similar field

• Minimum of 6 months of basic science lab research experience in one or more of the following areas: molecular biology, cell biology, and/or virology

• Is organized and attentive to details

• Prioritizes laboratory safety and scientific rigor

• Keeps accurate and complete records of experiments

• Works independently and with others as the situation requires

• Possesses excellent oral and written communication skills in English

Desired Qualifications*

Specific experience in any or all of the following research techniques:

• Microscopy (immunofluorescence, confocal microscopy)

• Protein expression in cultured cells by transient transfection and lentiviral transduction

• Virology (virus culture and titration)

• Molecular biology (DNA subcloning, PCR, qRT-PCR)

• Protein analysis (immunoprecipitation, SDS-PAGE, immunoblotting)

Additional Information

Laboratory research will be conducted onsite . Other research and laboratory management-related activities can be conducted remotely with approval of the laboratory principal investigator.

Background Screening

Michigan Medicine conducts background screening and pre-employment drug testing on job candidates upon acceptance of a contingent job offer and may use a third party administrator to conduct background screenings. Background screenings are performed in compliance with the Fair Credit Report Act. Pre-employment drug testing applies to all selected candidates, including new or additional faculty and staff appointments, as well as transfers from other U-M campuses.

Application Deadline

Job openings are posted for a minimum of seven calendar days. The review and selection process may begin as early as the eighth day after posting. This opening may be removed from posting boards and filled anytime after the minimum posting period has ended.

U-M EEO/AA Statement

The University of Michigan is an equal opportunity/affirmative action employer.

Job Detail

Job Opening ID

249493

Working Title

Research Laboratory Tech Assoc

Job Title

Research Laboratory Tech Assoc

Work Location

Ann Arbor Campus

Ann Arbor, MI

Full/Part Time

Full-Time

Regular/Temporary

Regular

FLSA Status

Nonexempt

Organizational Group

Medical School

Department

MM Int Med-Gastroenterology

Posting Begin/End Date

5/22/2024 - 7/05/2024

Career Interest

Research

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